个人简介：

　　冯凤琴，女，1964年10月生，博士研究生/工学博士，教授。浙江省食品添加剂协会专家委员会副主任委员，浙江省“151”第二层次人才，杭州市“131”第一层次人才，浙江省食品学会理事，浙江省生物工程学会理事，浙江省食品添加剂和配料协会理事。我校兼职硕士生导师。

　　研究方向：

　　新型食品添加剂及功能配料，食品生物技术。主要包括：

　　1.功能蛋白方向：以动植物蛋白为原料通过生物技术制备生物活性肽，涉及的功能包括促进矿物质吸收、提高免疫、降低过敏、降“三高”、抗疲劳、抗氧化、抗衰老、改善肠道等。除了研究功能肽的制备工艺、结构、功能特性外，还对其构效关系、工业化分离精制技术进行系统研究，取得了国内领先的技术成果。

　　2.功能脂类研究：（1）以植物油为原料，制备以1,3二油酸-2-棕榈酸甘油三酯(OPO)为主要成分的母乳脂肪替代油脂，研究内容涉及OPO的制备、OPO检测技术、应用技术及产品开发，还对制备OPO的关键酶（专一性及非专一性脂肪酶）的生产及应用技术进行研究。（2）在国内率先研究开发了兼具广谱抑菌功能和优良乳化性能的安全高效食品添加剂月桂酸单甘油酯(GML)，对高纯度GML的生产技术及GML在不同体系中的应用进行了系统研究；（3）在构效关系研究基础上，通过对中链脂肪酸的分子改性，筛选综合性能优越，符合食品应用要求的新型中链脂肪酸衍生物类乳化防腐剂，并进行产业化开发和应用。

　　学习工作经历：

　　1982-1986年，中国农业大学园艺系本科

　　1986-1989年，浙江农业大学食品系硕士 。

　　1989-1994年，杭州利民制药厂工程师

　　1994-1997年，无锡轻工大学博士

　　1998-2008，浙江大学食品系副教授

　　2008-    ，浙江大学食品系教授

　　2003年4～8月，加拿大奎尔夫大学访问学者

　　科学研究：

　　（1）国家自然科学基金委员会, 面上项目, 32072224, 基于肠道微生物组评估有机酸型食品防腐剂的安全性,2021-01-01 至 2024-12-31, 在研, 主持

　　（2）国家自然科学基金委员会, 面上项目, 31972079, PPARγ介导的月桂酸单甘酯对脂代谢的调控机理研究, 2020-01-01 至 2023-12-31,在研, 参与

　　（3）浙江省自然科学基金, 重大项目, LD19C200001, 基于肠道微生物组评估中链脂肪酸甘油酯类食品添加剂的安全性, 2019-01 至 2022-12, 已结题，主持

　　2022年发表论文：

1. Yan Chen, Yong Rui, Yuchao Wang, Minjie Zhao, Tao Liu, Jiachen Zhuang, Fengqin Feng*. Dietary glycerol monolaurate improves bone growth through the regulation of IGF-1 in the fish model, Food Bioscience, 2022, 50: 102119. (IF = 5.318, IF5.0=***)
2. Yue Wu, Jingjuan Yang, Chengmei Xu, Qiuqi Li, Yage Ma, Shenglan Zhao, Jiachen Zhuang, Fei Shen, Qianqian Wang, Fengqin Feng* and Xi Zhang*. Sea cucumber (Acaudina leucoprocta) peptides extended the lifespan and enhanced antioxidant capacity via DAF-16/DAF-2/SOD-3/OLD-1/PEPT-1 in Caenorhabditis elegans[J]. Frontiers in Nurtrition, 2022, https://doi.org/10.3389/fnut.2022.1065145. (IF =6.59, IF5.0=6.87)
3. Xianliang Luo, Wangxin Liu, Minjie Zhao, Tao Liu, Feifei Xiong, Lei Lei, Fuhuai Jia, Fengqin Feng*. A novel Atlantic salmon (Salmo salar) bone collagen peptide delays osteoarthritis development by inhibiting cartilage matrix degradation and anti-inflammatory, Food Research International, 2022, 162: 112148. (IF = 7.425, IF5.0=7.716)
4. Wangxin Liu, Xianliang Luo, Yang Tao, Ying Huang, Minjie Zhao, Jiahui Yu, Fengqin Feng*, Wei Wei*. Ultrasound enhanced butyric acid-lauric acid designer lipid synthesis: Based on artificial neural network and changes in enzymatic structure, Ultrasonics Sonochemistry, 2022, 88: 106100. (IF = 9.336, IF5.0=8.772)
5. Wang Qianqian, Shen Fei, Zhang Junhui, Cai Haiying, Pan Ya, Sun Tengjia, Gong Yihang, Du Juan, Zhong Hao*, Feng Fengqin*. Consumption of wheat peptides improves functional constipation: A translational study in humans and mice [J]. Molecular Nutrition & Food Research. 2022, 66(19): e2200313. (IF =6.57, IF5.0=6.88)
6. Wang Qianqian, Yang Zherui, Zhuang Jiachen, Zhang Junhui, Shen Fei, Yu Peng, Zhong Hao*, Feng Fengqin*. Anti-aging function of Chinese pond turtle (Chinemys reevesii) peptides through activation of the Nrf2/Keap1 signaling pathway and its structure-activity relationship [J]. Frontiers in Nutrition, 2022, 9: 961922. (IF =6.59, IF5.0=6.87)
7. Junhui Zhang, Huilin Yu, Hao Zhong, Qianqian Wang, Jun Tang, Fei Shen, Haiying Cai, Tao Liu, Fengqin Feng, Minjie Zhao*.Dietary emulsifier glycerol monodecanoate affects the gut microbiota contributing to regulating lipid metabolism, insulin sensitivity and inflammation. Food & Function, 2022, 13(17):8804-8817. (IF = 6.317, IF5.0=6.375)
8. Xianliang Luo, Wangxin Liu, Minjie Zhao, Ying Huang, Fengqin Feng*. Glycerol monolaurate beyond an emulsifier: synthesis, in vivo fate, food quality benefits and health efficacies. Trends in Food Science & Technology, 2022, 127:291-302. (IF = 16.002, IF5.0=17.835)
9. Minjie Zhao, Junhui Zhang, Tao Liu, Jing Wang, Haiying Cai, Xi Zhang, Quay Huai Xia, D., Fengqin Feng*, Jun Tang. Differential modulations of lauric acid and its glycerides on high fat diet-induced metabolic disorders and gut microbiota dysbiosis[J]. Food Research International, 2022, 157:111437. (IF = 7.425, IF5.0=7.716)
10. Hao Zhong, Jinyuan Shi, Junhui Zhang, Qianqian Wang, Yipeng Zhang, Peng Yu, Rongfa Guan*, Fengqin Feng*. Soft-shelled turtle peptide supplementation modifies energy metabolism and oxidative stress, enhances exercise endurance, and decreases physical fatigue in mice[J]. Foods, 2022, 11(4):600. (IF = 5.561, IF5.0=5.94)
11. Wei Chen, Xiaodong Zheng, Fengqin Feng, Chengfu Lou, Haoxin Cui. Exploration and practice of "Five-in-One" hybrid teaching model of the national top-class undergraduate course "Food Safety". Food and Fermentation Industries[J]. 2022, 48(01):330-334. (IF = 1.848, IF5.0=1.505)
12. Wangxin Liu, Xianliang Luo, Tao Liu, Fengqin Feng*. Study on the digestive characteristics of short-and medium-chain fatty acid structural lipid and its rapid intervention on gut microbes: In vivo and in vitro studies. Food Chemistry, 2022, 380:131792. (IF = 9.231, IF5.0=8.795)
13. Jing Wang, Huiqi Jiang, Yasmin Alhamoud, Yong Chen, Jiachen Zhuang, Tao Liu, Luyun Cai, Weiliang Shen, Xiongfei Wu, Weiqiang Zheng, Fengqin Feng*.Integrated metabolomic and gene expression analyses to study the effects of glycerol monolaurate on flesh quality in large yellow croaker (Larimichthys crocea)[J]. Food Chemistry, 2022, 367:130749. (IF = 9.231, IF5.0=8.795)*
14. Jiachen Zhuang, Abdullah, Yuchao Wang, Weiliang Shen, Weiqiang Zheng, Tao Liu, Jing Wang*, Fengqin Feng*. Evaluating dynamic effects of dietary glycerol monolaurate on the productive performance and flesh quality of large yellow croaker (Larimichthys crocea)[J]. Food Chemistry, 2022, 387:132833. (IF = 9.231, IF5.0=8.795)*
15. Jing Wang , Yong Chen , Hao Zhong , Fang Chen , Joe Regenstein , Xiaosong, Hu , Luyun Cai*, Fengqin Feng*.The Gut Microbiota as a Target to Control Hyperuricemia Pathogenesis: Potential Mechanisms and Therapeutic Strategies[J]. Critical Reviews in Food Science and Nutrition, 2022, 62(14):3979-3989. (IF = 11.208，IF5.0=12.104)
16. 王倩倩,杜鹃,冯凤琴.海参肽对大鼠乙酸性胃溃疡愈合的促进作用[J].中国食品学报,2022,22(08):109-117.
17. 阮圣玥,刘滔,莫秋芬,冯凤琴.食品防腐剂对肠道菌群和宿主健康的影响研究进展[J/OL].食品科学:1-11[2022-10-03].
18. 骆贤亮,刘旺鑫,王晶,杜鹃,冯凤琴.海参肽与肉苁蓉组合物对急性运动小鼠激素水平及睾丸抗氧化损伤的影响[J/OL].浙江大学学报(农业与生命科学版):1-12[2022-10-03].
19. 吴俊豪,王晶,KHO SETHYKUN,覃川,王倩倩,余鹏,冯凤琴.龟肉蛋白肽延缓果蝇衰老的作用及机制研究[J].食品工业科技,2022,43(17):394-401.
20. 王倩倩,杜鹃,冯凤琴.不同水解度酪蛋白磷酸肽的理化性质和持钙能力比较[J].食品安全质量检测学报,2022,13(05):1438-1443.
21. 杨环毓,杨露西,潘绿昌,冯凤琴.大豆未消化蛋白的功能性质研究[J].食品安全导刊,2022(06):108-110+114.
22. 骆贤亮,晏永球,冯凤琴.牡蛎肽与人参提取物配伍提高雄性小鼠性功能及抗疲劳作用研究[J].食品工业科技,2022,43(01):366-374.

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